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YC S26: Who Are the 23 Healthcare Startups?
Heli Vora · Founding GTM
YC S26's healthcare companies span care operations, patient-data infrastructure, insurance, research and life sciences.
For products that need to exchange information with EHRs or payer portals, integration is a practical part of deployment. Tross provides APIs that help healthcare teams connect to those systems.
For teams choosing the infrastructure behind those workflows, see our comparison of API platforms for EHRs and payers.
The table below lists 23 healthcare companies from YC's S26 batch, their founders, and what they are building. Each company name links to the official website listed on its YC profile.
Healthcare startups from YC S26
Company | Founders | What they are building |
|---|---|---|
Campbell Mercer-Butcher and Max Shand | AI-powered operating system for radiology networks, automating patient scheduling and communications. | |
Prabha Dublish and Aaron Leon | Intelligence layer for patient information, pulling a patient's full medical history from every provider via one API. | |
Melvin Chen | AI agents that run primary healthcare clinic operations, from document filing to phone calls. | |
Maryam Jahed and Seak Meng Lay | AI-native, full-stack radiology practice rebuilding clinical and operational workflows with agents. | |
Paul Steven Conyngham | Personalized mRNA cancer vaccine platform, starting with dogs. | |
Maryanne Alhallak and Anthea Guo | At-home skin-tracking device and AI platform, described as the "Oura Ring for skin." | |
Lloyd Armbrust and Emily Colman | AI that personalizes peptides and GLP-1s (like Ozempic) to your biology using labs and wearables. | |
Jack Beecher | Dental-benefits company that sells plans directly to employers and uses AI to process claims. | |
Alfredo Gonzalez, PhD and Ranad Humeidi, PhD | A personalized research lab built around one patient, tackling complex cancer cases with AI and genomics. | |
Eta Atolia, MD, PhD | Platform that develops personalized or population-level vaccines for any cancer or infection in weeks. | |
Asaph Kupferman and Jonah Kaye | Platform that lets healthcare teams describe and deploy HIPAA-compliant internal tools connected to production data. | |
Bryan Chung and Chang Lu | AI-native decision infrastructure for health insurance, turning denied claims into source-cited, physician-attested appeals. | |
Anis Mihrshahi and Leon Mojarrabi | Personalized probiotics, sequencing your gut microbiome to predict which strains will actually colonize, guaranteed. | |
Sanjukta B. and Shaamil Karim | Foundation models trained on pre-clinical and clinical data to predict how a patient will respond to a drug in clinical trials. | |
Abraham Heifets | Extrapolative AI that discovers oral, pill-form alternatives to injectable drugs like insulin and GLP-1s. | |
Paridhi Latawa, Frank Lee and Jin Wong | 24/7 AI health and longevity companion that fuses your wearables, blood panels, and genomic data into one text-based coach. | |
Jordan Ibe and Ansh Tandon | AI-native home care agency in Michigan, running the entire back office on agents to pay caregivers more and help families get paid. | |
Rishab Jain and Aditya Jain, MD | AI-run health benefits platform for employers, steering patients toward lower-cost care trajectories to cut healthcare spend 20-50%. | |
Jacob Chia and Sid Unnithan | Voice agents that accelerate care coordination for workers' comp managed care orgs, replacing phone, fax, and email handoffs. | |
Ayush Chauhan and Daood Hashmi | An AI platform that runs any chemistry task end to end, from literature search to running the calculations itself. | |
Amie Leighton and Saroosh Khan | Full-stack, AI-native clinical group for mental health that brings independent practices into one national clinical group. | |
Raj Jagiasi and Vihaan Jagiasi | AI voice agents that run the front office for healthcare practices, handling patient calls and completing workflows inside the EHR. | |
Anish Mariathasan and Ayush Patel | Medical and biological datasets, evaluations, and reinforcement learning environments for training more capable and aligned health AI models. |
Frequently asked questions
How many healthcare startups are in YC S26?
This list includes 23 companies from YC's Summer 2026 batch whose products serve healthcare, health insurance, life sciences, or health-AI use cases.
How many of the YC S26 healthcare startups explicitly use AI?
Eighteen of the 23 companies explicitly describe their product as using AI, agents, foundation models, or AI-enabled workflows. The remaining companies span data infrastructure, vaccines, microbiome science, and other healthcare products.
Which healthcare areas are represented in YC S26?
The cohort spans provider operations, radiology, mental health, health insurance and benefits, patient-data infrastructure, consumer health, diagnostics, biotech, drug discovery, and health-AI infrastructure.
Which YC S26 companies are focused on provider operations and care delivery?
Avoca Systems, Care GP, Radley, Cova, Allia Health, Elite, and Evergrove focus on workflows used by practices, clinics, home-care agencies, or care-coordination organizations.
Which YC S26 companies are focused on health insurance and benefits?
Denta sells dental-benefit plans, Insurf works on denied-claim appeals, and Prescience builds an employer health-benefits platform. Each addresses a different part of how coverage is delivered or managed.
Which YC S26 companies are building consumer or personalized-health products?
Lumeria, RonanRX, Illume Labs, and GutGutGoose use personal health data, tests, wearables, or the microbiome to support more individualized health decisions.
Which YC S26 companies are working on research, biology, or drug development?
Gamgee Technologies, Omanta, TareBio, Atlas Discovery, WonderTx, Rasyn, and Osseus are developing tools or platforms for vaccines, cancer, biology, chemistry, clinical research, or health-AI model development.
How are the companies in this YC S26 healthcare list categorized?
Each company is placed according to its publicly stated product focus. Some companies could reasonably fit more than one category, so the categories are a guide to the cohort rather than a rigid industry taxonomy.
Connecting healthcare products to existing systems
For teams building around patient records or insurance workflows, access to EHR and payer data is part of getting the product into use. Tross provides APIs for EHRs and payer portals, helping healthcare teams connect their products to the systems their customers already use.
Building for a specific specialty? See our oncology EHR guide and behavioral health EHR guide.
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